Compile Data Set for Download or QSAR
maximum 50k data
Found 17 of kd for Serotonin (5-HT) receptor
having polymerids = 2152,3427,3428,3737,49000035,49000077,49000089,49000102,49000109,6548,7150,8334 and
complexids = 50004311,50009873
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Affinity DataKd:  1.5nMAssay Description:Binding affinity against 5-hydroxytryptamine 1D receptor beta using rabbit saphenous vein assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50122872(4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...)
Affinity DataKd:  2nMAssay Description:Binding affinity to 5-HT4 receptor (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50092543(4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pyrim...)
Affinity DataKd:  0.700nMAssay Description:,Antagonism of stimulation of 5-hydroxytryptamine receptor on the L-type calcium current (I Ca) in isolated human atrial myocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM29525(3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 1...)
Affinity DataKd:  15.8nMAssay Description:Binding affinity to human 5HT4 receptor expressed in HEK293 cells by saturation binding methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50288284(4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-iodo-2-...)
Affinity DataKd:  2.60nMAssay Description:Compound was tested for its binding affinity towards 5-HT-3 receptor in whole rat brain using (S)-[125I]-zacopride as the radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50000492((zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl...)
Affinity DataKd:  0.600nMAssay Description:Compound was tested for its antagonistic activity against 5-hydroxytryptamine 3 receptor in rat brain using [3H]-zacopride as the radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50288285(CHEMBL90314 | N-(S)-1-Aza-bicyclo[2.2.2]oct-3-yl-5...)
Affinity DataKd:  0.150nMAssay Description:Compound was tested in vitro for its antagonistic activity against 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50423297(CHEMBL251541 | Obelin)
Affinity DataKd:  112nMAssay Description:Binding affinity to human 5HT1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224303(CHEMBL283686)
Affinity DataKd:  8.40E+3nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligand, activity is expressed as Kd.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224302(CHEMBL31783)
Affinity DataKd:  43nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor using 1 uM LSD as masking ligand, activity is expressed as Kd.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224305(CHEMBL285355)
Affinity DataKd:  8.40E+3nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligand, activity is expressed as Kd.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM21392(3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...)
Affinity DataKd:  1.60nMAssay Description:Binding affinity for 5-hydroxytryptamine 1D receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKd:  13nMAssay Description:Binding affinity for 5-hydroxytryptamine 1D receptor was determinedMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKd:  32nMAssay Description:Binding affinity for 5-hydroxytryptamine 1C receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM21392(3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...)
Affinity DataKd:  631nMAssay Description:Binding affinity for 5-hydroxytryptamine 1C receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM85099(CAS_141474-54-6 | SDZ SER 082 FUMARATE | SDZ SER-0...)
Affinity DataKd:  3.98E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex membranes using [125]ICYPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Affinity DataKd:  1.5nMAssay Description:Binding affinity against 5-hydroxytryptamine 1D receptor beta using rabbit saphenous vein assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank